tina huang data scientist

Libraries showing a mitochondrial or nuclear contamination rate over 10% were considered substantially contaminated whereas those between 5 and 10% were considered marginally contaminated and were treated differently (details are provided in Supplementary Information, section3). Tina has 11 jobs listed on their profile. There is no biographical data to display. At this startup dedicated to b2b marketing, we, the data team formed by 2 people, are organizing all the data from zero and looking for their real value. The similarity between Goyet Q116-1 and Goyet Q376-3 and the Fournol cluster is also observed at the mtDNA level, with both groups including individuals who carried mtDNA haplogroup M, which has not been found in European individuals from after the LGM24 (Extended Data Figs. Genome Biol. The mtDNA contamination was estimated by Schmutzi (--notusepredC --uselength)69 for all the libraries. Curr. Finally, we estimated the genetic diversity of Epigravettian-associated individuals in the dataset by calculating both pairwise mismatch rates (PMR) on pseudo-haploid genotypes and individual heterozygosity levels on pseudo-diploid genotypes (Supplementary Data 3.A). T.T., D.C. and E.A. Gamble, C., Davies, W., Pettitt, P., Hazelwood, L. & Richards, M. The archaeological and genetic foundations of the European population during the Late Glacial: implications for agricultural thinking. Claim Author Page. The oldest genomes carrying ancestries that derive primarily from the lineage leading to present-day Europeans are Kostenki 14 (from 37ka, with uncertain archaeological association from western Russia), Goyet Q116-1 (35ka, Aurignacian-associated from Belgium) and Bacho Kiro 1653 (35ka, probably Aurignacian-associated from Bulgaria)2,4,8. The grouping of Epigravettian-associated populations is shown with the same colour in a. Danielle Fishel. 26 and Supplementary Data 2.H). Typically, it calls for a great deal of data heavy-lifting and data visualizations with SQL and Python or R. A number of things can be done with traditional analysis, but it is machine learning that has taken an extremely solid place in product development. 276, 107319 (2022). ISSN 1476-4687 (online) 2011. Follow. 2010, pdb.prot5448 (2010). Fifth, the Oberkassel ancestry in western and central Europe and the Sidelkino ancestry in eastern Europe remained largely isolated for almost 6,000 years until genetic interactions were first observedaround 8ka in northeastern Germany, possibly associated with cultural exchanges along the Baltics49 and around 7.5ka in the upper Volga region, possibly linked to the spread of pottery in the region50. 2932 and Supplementary Table 4). Follow a proven methodology, discover how to avoid common mistakes and impress employers as the best person for the job. The genetic history of Ice Age Europe. Lipson, M. et al. Int. ScienceDaily, 1 March 2023. AMAZING COURSE! Int. Compared with the genetic diversity observed among all analysed Gravettian-associated groups, Epigravettian-associated individuals show significantly lower amounts of genetic diversity (two-tailed t-test, P<0.001) (Fig. Tina teaches SQL in data science in addition to this basic material. Le palolithique suprieur en Italie. 1 and 2). Join a growing community of 11K+ to find accountability partners, take part in productivity sprints, and join discord only events! It encourages me to go out and re-learn SQL and excites me for the mock interviews to come. Highly recommended for not only people preparing for interviews but for people that just want to improve their coding skills. My name is Tina and I'm a data scientist and YouTuber. Posth, C., Yu, H., Ghalichi, A. et al. Nature 551, 368372 (2017). 9) and testing the relative affinity among them using f4-statistics in the form f4(Mbuti, Epigravettian A; Epigravettian B, Epigravettian C) (Supplementary Data 2.E). Billed once. The sample size of individualpairsincluded in each groupis reported in SupplementaryData 3.A. All Rights Reserved. Nucleic Acids Res. The tree was calculated on 16,528 positions (partial deletion 95%) and with 500 bootstrap iterations using MEGA1097. Pleistocene mitochondrial genomes suggest a single major dispersal of non-Africans and a Late Glacial Population turnover in Europe. Ice Age survivors. Int. Along with pushing for more accessibility, she also creates content around working in the tech industry, the challenges that come with it, and career advice. Hi, my name is Tina and I'm a data scientist at a FAANG company. Contrary to the proposal in Fu et al.4 but in agreement with Petr et al.17, we do not observe a substantial decrease of Neanderthal ancestry in most European hunter-gatherers through time (Supplementary Information, section6 and Supplementary Figs. Currently use of the word 'vape' now means "to inhale and exhale the vapor produced by an . Piezonka, H. et al. 7,794 followers. We thus modelled individuals belonging to the GoyetQ2 cluster and El Mirn as a mixture between the Fournol 85 and Arene Candide 16 genomes as proxies to represent the Fournol and Villabruna ancestries, respectively, in Magdalenian-associated groups (Fig. However, the research team found no evidence for this, on the contrary: hunter-gatherer populations associated with the Gravettian culture and living in central and southern Europe are no longer genetically detectable after the LGM. mtDNA capture63 was also performed for those libraries where mtDNA coverage was not high enough to assess mtDNA haplogroup and contamination. Become the most confident candidate in the room. Initial Upper Palaeolithic humans in Europe had recent Neanderthal ancestry. Upper Palaeolithic genomes reveal deep roots of modern Eurasians. Life and career Early life. F-statistics suggest that Le Piage II is genetically intermediate between Fournol 85 and El Mirn (Supplementary Data 2.D). Hi! Kozowski, S. K., Potowicz-Bobak, M., Bobak, D. & Terberger, T. New information from Maszycka Cave and the Late Glacial recolonisation of Central Europe. ADS 4, 324333 (2020). In this video, I had the opportunity to talk with Tina Huang, a Data Scientist at one of the FAANG companies. To bind DNA, silica columns for high volumes (High Pure Viral Nucleic Acid Large Volume Kit (Roche)) were used. A dashed line of 50 cM total ROH is drawn in each panel to help comparison between panels with different y-axis scales. Ice Age survivors. Individuals from northwestern Italy (Arene Candide 16), central Italy (Continenza) and Sicily fall on a phylogenetically more derived branch (group 2), which further diversified into a branch composed of Sicilian hunter-gatherers only (group 3). The ancient human specimens analysed in this work derive from multiple scientific collaborations. PLoS ONE 14, e0217996 (2019). Gonzlez-Fortes, G. et al. Hi! F4-statistics further support this view, revealing that Le Piage II is more closely related to the Fournol clusterthan the Vstonice cluster (f4(Mbuti, Le Piage II; Vstonice, Fournol 85)0, Z=6.58). However, one of my favorites is using supervised learning techniques, such as random forest, SVM, and XGBoost, to discover which features contribute the most to the success of a product. Mittnik, A. et al. Content on this website is for information only. Here we analyse 356 ancient hunter-gatherer genomes, including new genomic data for 116 individuals from 14 countries in western and central Eurasia, spanning between 35,000 and 5,000 years ago. Gravettian cranial morphology and human group affinities during the European Upper Palaeolithic. Google Scholar. - Developing a high . Alexis Bledel. Curr. The Neolithic transition in the Baltic was not driven by admixture with early European farmers. 9). (Robert Rueda; Tina Saldivar; Lynne Shapiro; Shane Templeton; Houghton Mifflin Company Staff) 2022-112-4f84b - Ecologizr. In spite of growing discussions about its nature27,28, the Epigravettian culture has been traditionally assumed to be the result of a transition from the preceding local Gravettian29. 4, 11 (2007). Tina has an MSc in Computer Science from the University of Pennsylvania, and an HBSc in Pharmacology from the University of Toronto. Next, we investigated the genetic relationships between Epigravettian-associated individuals across the Italian peninsula, by reconstructing a phylogeny based on a matrix of pairwise f2 genetic distances (Fig. I am Tina Huang, PhD, a data scientist, and the director of the Data Science Learning Center at the University of Arizona. | pros vs cons. Author pages are created from data sourced from our academic publisher partnerships and public sources. Pleistocene North African genomes link Near Eastern and sub-Saharan African human populations. Jobs People Learning Dismiss Dismiss. Nat. It will provide you with confidence and methodology for demonstrating the required skills appropriately. Evol. 13). Internet Explorer). 26, 827833 (2016). This is one of the things that make us stand out from other platforms which usually consider mathematics and statistics a prerequisite. Sep 2017 - Aug 20181 year. Instead, for the two SNPs associated with skin colour (SLC24A5 (rs1426654) and SLC45A2 (rs16891982)), Sidelkino clusterand Ukraine HG groups show a higher frequency (>90% for SLC24A5 and 2961% for SLC45A2) of the derived alleles related to light skin colour, compared with Oberkassel and Villabruna clusters, where those alleles are almost completely absent (<1%). 3b). The mapped reads from the same individual and library set-up were merged and duplications were removed with DeDup. Charlene Hunter is a developer and an incredible advocate for increasing diversity in tech. Fab Business Solutionsis a ProfessionalNewsPlatform. After merging, individuals with less than 6,000 SNPs on 1240k sites were excluded from further analysis because of low coverage. As a Graduate and Consultant in the Business Tax Advisory (Financial Services) team, I provided tax advice and tax compliance services to organisations in the banking and capital markets, wealth and . The ancestry found in individuals associated with the preceding Aurignacian culture from central Europe (GoyetQ116-1ancestry) gave rise to Gravettian-associated individuals from western and southwestern Europe. 4a). Google Scholar. Extended Data Fig. Taipei, Taiwan . We detect the highest amount of ROHs in Epigravettian-associated individuals from Sicily, who carry an extreme amount of more than 200cM of short ROHs (48cM). ScienceDaily. In conclusion, our study reveals that western and southwestern Europe served as climatic refugia for the persistence of human groups during the coldest phase of the last Ice Age whereas populations in the Italian peninsula and the eastern European plain were genetically overturned, challenging the role of these regions as glacial refugia for humans. This derived ancestrythe Fournol clustersurvived during the LGM in Solutrean-associated individuals, possibly within the Franco-Cantabrian climatic refugium25, leading to later populations associated with the Magdalenian culture (GoyetQ2 cluster and El Mirn). PubMed de Investigacin en Arqueologa y Patrimonio Histrico, University of Alicante, Sant Vicent del Raspeig, Alicante, Spain, Javier Fernndez-Lpez de Pablo&Magdalena Gmez-Puche, Amsterdam Centre of Ancient Studies and Archaeology, University of Amsterdam, Amsterdam, The Netherlands, Department of Anatomy, Histology and Anthropology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania, Service Rgional de lArchologie de Bourgogne-Franche-Comt, Besanon Cedex, France, Laboratoire de Chrono-Environnement, UMR 6249 du CNRS, UFR des Sciences et Techniques, Besanon Cedex, France, Institute of Pre- and Protohistory, University of Tbingen, Tbingen, Germany, Department of Archeological Sciences, Thuringian State Office for Monuments Preservation and Archeology, Weimar, Germany, University of Bucharest, Faculty of Geology and Geophysics, Department of Geology, Bucharest, Romania, Institute for Advanced Studies in Levant Culture and Civilization, Bucharest, Romania, German Archaeological Institute, Berlin, Germany, Brandenburg Authorities for Heritage Management and Archaeological State Museum, Zossen, Germany, Institute for Pre- and Protohistory, Kiel University, Kiel, Germany, Institute of Archeology at Brno, Czech Academy of Sciences, Centre for Palaeolithic and Paleoanthropology, Brno, Czechia, Institute of Archaeology, Academy of Sciences of the Republic of Tatarstan, Kazan, Russia, Samara State University of Social Sciences and Education, Samara, Russia, Early Prehistory and Quaternary Ecology, Department of Geosciences, University of Tbingen, Tbingen, Germany, Paleoanthropology, Institute for Archaeological Sciences, Department of Geosciences, University of Tbingen, Tbingen, Germany, DFG Centre for Advanced Studies Words, Bones, Genes, Tools, University of Tbingen, Tbingen, Germany, Royal Belgian Institute of Natural Sciences, Brussels, Belgium, Institute of Archaeology Russian, Academy of Sciences, Moscow, Russia, School of Archaeology, University of Oxford, Oxford, UK, Peter the Great Museum of Anthropology and Ethnography (Kunstkamera), Russian Academy of Sciences, Saint Petersburg, Russia, Department of Cultures, University of Helsinki, Helsinki, Finland, Seminar for Pre- and Protohistory, Gttingen University, Gttingen, Germany, Lower Saxony State Service for Cultural Heritage, Hannover, Germany, Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands, You can also search for this author in Biol. Utilized python and R on high performance computing Linux cluster to discover 3 new cancer mutations. Save my name, email, and website in this browser for the next time I comment. 1c). PubMed iScience 25, 104244 (2022). Check out The data science resume that got me my FAANG job and subscribe to Tina Huangs YouTube channel. We identify a genetic ancestry profile in individuals associated with Upper Palaeolithic Gravettian assemblages from western Europe that is distinct from contemporaneous groups related to this archaeological culture in central and southern Europe4, but resembles that of preceding individuals associated with the Aurignacian culture. One-time payment. Itchy Eyes and a Runny Nose? Front. Genetics and material culture support repeated expansions into Paleolithic Eurasia from a population hub out of Africa. The data here can also be structured or unstructured. Este botn muestra el tipo de bsqueda seleccionado. 10 and 11). Find contact's direct phone number, email address, work history, and more. This suggests that genetic links between southern and southwestern European hunter-gatherers around the time of the LGM extended north of the Pyrenees. Protoc. Tina Huang I'm a data scientist, youtuber, and the first Lonely Octopus . First, we show that individuals associated with the Gravettian culture across Europe were not a biologically homogeneous population. After the LGM, the Epigravettian culture was widespread in southern andsoutheastern Europe. First Name Tina #39. USA 117, 1279112798 (2020). Required fields are marked *. Nature 582, 384388 (2020). The deduplicated bam files were filtered using PMDtools 0.6068 with a threshold of 3, to reduce potential modern DNA contamination based on postmortem DNA deamination. YourCourse Certificatehas no expiration date. View Tina Zhang's business profile as Brand Specialist at Dymind Biotechnology. Late Upper Palaeolithic hunter-gatherers in the Central Mediterranean: new archaeological and genetic data from the Late Epigravettian burial Oriente C (Favignana, Sicily). W jednej z historii misiaczki za rad pewnej wydry zamieszkuj w tajemniczym domostwie. Epoxy Flooring UAE; Floor Coating UAE; Self Leveling Floor Coating; Wood Finishes and Coating; Functional Coatings. Radiocarbon 62, 725757 (2020). Saag, L. et al. wrote the manuscript with input from T.T., E.A., W.H., J. Krause and all other co-authors. The increasing level of admixture between distinct hunter-gatherer populations from around 8ka onwards indicates an intensified mobility of those forager groups. Ecol. It is often considered as a pan-European cultural mosaic with regional variations in material to symbolic productions20,21. We then removed samples with less than 0.04X coverage (calculated on the mappable, non-recombining region of the Y chromosome98) to avoid arbitrarily placing low-coverage samples at the root of major haplogroups. 116, 105100 (2020). The PCA was calculated with 1379 individuals from 87 western Eurasian modern populations on the 1240k_HO dataset, which was intersected between the 1240k and Human Origins datasets (Supplementary Data 1.K). Nature 505, 8791 (2014). Folding bicycle. Fourth, we extend the finding of a large-scale genetic turnover as early as 14ka in central and western European hunter-gatherers associated with multiple techno-complexesFedermesser, Azilian and other Final Palaeolithic groups4despite considerable technological continuity with the preceding late Magdalenian. About the author: Tina Huang is a data scientist at one of the FAANG companies. Billed once. Tina Huang Data Scientist. Teaching Assistant. Google Scholar. Using Y-chromosome capture enrichment to resolve haplogroup H2 shows new evidence for a two-path Neolithic expansion to Western Europe. The bivariate plots show the expansion of Oberkassel and Sidelkino ancestries through time in two European areas (longitude below and above 30 degrees). Furthermore, the findings show that there had been no genetic exchange between contemporaneous hunter-gatherer populations in western and eastern Europe for more than 6,000 years. . Genome Biol. We applied ANGSD 0.93470 and hapCon71 for libraries from male individuals, and applied contamLD72 and a newly developed method that analyses contamination in ROH for female and male libraries (see Supplementary Information, section2 for a detailed description). Quat. While terms such as lithic industry, techno-complex, prehistoric tradition, and so on might be more appropriate to refer to the various associated chrono-cultural subdivisions, they concern different levels of discussion and are not applicable to all contexts investigated here. What is a Scatterplot in Data Visualization, Machine Learning in R: Building a Classification Model. We provide five novel insights into the genomic history of hunter-gatherer populations over a time span of 30,000 years from the Upper Palaeolithic to the Neolithic. This figure shows that the Gravettian-associated individuals from western Europe (Fournol cluster) are closely related to Goyet Q116-1 while the Gravettian-associated individuals from central-eastern and southern Europe (Vstonice cluster) are closely related to the Sunghir group, representative of the Kostenki cluster. under exclusive license to Springer Nature Singapore Pte Ltd. 2022 R. Huang et al. 2, 17561762 (2007). de Lige, 2021). We also genotyped a selection of previously published individuals with the same approach (Supplementary Data 1.G)2,4,30,74,75,76,77,78. From around 8ka, we begin to observe admixture events with Sidelkino ancestry in central Europe. Present-day individuals (gray dots) genotyped on theHumanOrigins dataset are used to define the PCA variation onto which ancient genomes (coloured symbols) are projected. You can also check out our video on the topic below or scroll down to keep on reading. Limits of long-term selection against Neandertal introgression. Bioinformatics 20, 289290 (2004). This finding, in conjunction with the genetic affinity of the Villabruna cluster to ancient and present-day Near Eastern ancestries4,15,16 (Supplementary Information, section8, Supplementary Fig. Our analyses demonstrate that the Fournol cluster is a better source for Magdalenian-associated genomes than Goyet Q116-1. H. Rougier received support from the College of Social and Behavioral Sciences of CSUN and the CSUN Competition for RSCA Awards. Xiamen Guansheng Precision Machinery Co Ltd is a company integrating R&D, production and sales. This is perfect for those of us who haven't a clue what to expect from data science - SQL portion - interviews. Natl Acad. Some of those early groups from more than 40ka further admixed with Neanderthals, as shown by signals of recent introgression in individuals from Bacho Kiro in Bulgariaassociated with an Initial Upper Palaeolithic (IUP) archaeological cultureand from Petera cu Oase in Romania2,6. In panel a, genetic affinity between different ancestries is indicated by thick lines or shades, while admixture is indicated with arrows. The responsible co-authors for the material from each archaeological site are listed in Supplementary Information, section 1. Nature 555, 197203 (2018). Publications. The nuclear DNA contamination was estimated with several methods. But she came up with a way to break down the code and create a website that she was proud of. We use cookies to improve your experience and give you personalized content. Bioinformatics 25, 20782079 (2009). 27, 32023208.e9 (2017). "Ice Age survivors." Details of the grouping and ROH segments are provided in Data S3.B. In no time, she established herself as one of the favorite vloggers of the data community. & Dolukhanov, P.) 122145 (Avebury, 1993). Trzej niedwiedzi braciszkowie przeywaj swoje dziecistwo, pakujc si w najrozmaitsze tarapaty za spraw magicznego pudeka. The code for the newly developed ROH based contamination estimate method is available at https://github.com/hyl317/hapROH. Great content - Tina is all class and an excellent instructor. Nucleic Acids Res. Sci. The nucleolus is the largest substructure in the nucleus, where ribosome biogenesis occurs. Besides El Mirn, who has around 43% Villabruna ancestry, all other Magdalenian-associated individuals have a lower proportion of this component (1929%) and can thus be assigned to the GoyetQ2 cluster (Fig. These results show that some, but not all, of the genomic ancestries present in Europe between around 40ka and 30ka survived in the Gravettian-associated populations studied so far. Follow Author. 3a and Supplementary Fig. Data warehousing is a relatively new field that focuses on the use of large datasets for analytical purposes. 19-78-10053). Amazing content! Google Scholar. Article Tina Huang is a well-known data scientist who has over 10 years of experience on YouTube and has previously worked at a FAANG organization. The ROH segments in hunter-gatherer genomes were identified using hapROH101. 7,794 Followers, 14 Following, 9 Posts - See Instagram photos and videos from Tina Huang (@hellotinah) hellotinah. Int. 2023 365 Data Science. Showcase your skills and bolster your data science credentials. Olalde, I. Her YouTube channel is dedicated to data and computer science, including how to educate yourself in these topics. 5, 820825 (2021). Slider with three articles shown per slide. 25, 459466 (2015). Lifetime access to all course materials and updates. This, together with the evidence of Villabruna ancestry in El Mirn 19ka, further suggests that this genetic discontinuity could be the result of palaeogeographic and palaeoecological transformations connected to the LGM32, rather than to the BllingAllerd warming period4,15 (14.712.9ka).

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